#1 — President John F. Kennedy’s father — Joseph Patrick Kennedy, Sr. — suffered an extremely debilitating stroke, including aphasia where he could not speak, on December 19, 1961. Henceforth, Joe Senior was unable to reign in his newly rebellious son knowing that his assassination was inevitable.
“On December 19, 1961, at the age of 73, Kennedy suffered a stroke. He survived, but was left paralyzed on his right side. Thereafter, Kennedy suffered from aphasia, which severely affected his ability to speak.”
(Source: Joseph P. Kennedy Sr.)

But why did JFK suddenly turn into a rebel against the New World Order globalist agenda? See #2 below.
#2 — During his term as POTUS, JFK, on two occasions, did LSD in the White House, which was secretly brought to him by Mary Pinchot Meyer—a friend he originally met at Choate School in the late 1930s. As follows:
JFK did acid supplied by Mary Meyer whose husband was Cord Meyer—the head of the CIA’s International Organizations Division
Those highly transformative drug experiences completely altered JFK’s understanding of reality and future outlook to the point where he began acting out of a distinctly higher level of conscience. This newfound sense of moral responsibility compelled him to work with Soviet Union President Nikita Khrushchev to resolve the Cuban Missile Crisis swiftly and without violence behind the scenes. Of course, the U.S. Intelligence Community was furious with JFK’s back channeling with the Kremlin and even murdered his primary go-between — Marilyn Monroe — whose code name was “Masha” earlier that same year in order to prevent her facilitation of defusing that crisis.
“Marilyn Monroe’s relationship with both JFK and RFK were the subject of much rumor and speculation. The true nature of these relationships, especially her interaction as “Masha” with the KGB, proved to be of great help to the Kennedys, particularly in opening up critical channels of information with the Soviet Union prior to and during the resolution of the Cuban Missile Crisis. Marilyn Monroe was assassinated on August 5 by the C.I.A. over 2 months before the worst phase of the crisis occurred in October of 1962.”
(Source: John F. Kennedy: The “Scarlet Pimpernel” of the 20th Century)